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Under the licensing agreement, Yao Pharma would grant Pfizer an exclusive worldwide licence for the development, use, manufacturing and commercialisation of oral small-molecule drugs known as GLP-1 receptor agonists, including YP05002, as well as any products containing such compounds as an active ingredient, according to a statement by Fosun on Tuesday.
GLP-1 therapies have become a competition focus in the global pharmaceutical market, with injectable drugs like Novo Nordisk’s Wegovy and Ozempic, and Eli Lilly’s Zepbound and Mounjaro generating billions of dollars in annual revenue.
The licensed drug candidate YP05002 is undergoing Phase 1 clinical development in Australia for chronic weight management.
Yao Pharma is expected to receive an upfront payment of US$150 million and become eligible for milestone payments of up to US$1.9 billion tied to development, regulatory and commercial achievements, plus tiered royalties on future sales.
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